For centuries, people have sought natural remedies to boost their overall health and vitality. This has led to the discovery of a few notable supplements with impressive medicinal properties - Lion's Mane, Cordyceps, and CBD. 

These three supplements have all been linked to different health benefits, including improved cognitive functioning1, enhanced energy levels2, and better overall well-being3. But how do these three supplements compare to each other? 

This article covers the answer to this question and more! We'll explore the similarities and differences between Lion's Mane, Cordyceps, and CBD, as well as the potential health benefits and side effects of each. We'll also discuss the best way to take these natural supplements and provide some helpful tips for choosing the best one for your needs. 

However, before we dive into the specifics of each supplement, it's important to note that each product can vary significantly depending on where it's sourced from. That's why you should consider BATCH for all your supplement needs. We offer premium CBD products that are crafted with high-quality ingredients and lab-tested to ensure purity and potency. From our CBD gummies and oils to our softgels and topicals, we have something for everyone. 

So, visit our shop today and get started with our powerful cannabinoids. 

Let’s get started!

What Is Lion's Mane? 

Also known as Yamabushitake or Hou Tou Gu, Lion's Mane is a type of mushroom valued for its medicinal properties. It has a unique appearance, resembling the mane of a lion, hence its name. This mushroom grows on dead or dying trees and logs, and can often be found in the wild. 

Lion's Mane Health Benefits 

For a long time, Lion's Mane has been used in traditional Chinese medicine to treat various conditions4, and this mushroom is now gaining attention in the modern world for its potential health benefits. 

Several studies suggest that it can help: 

  • Improve cognitive function1 
  • Relieve anxiety and depression5 
  • Reduce inflammation6 
  • Boost the immune system7 
  • Manage diabetes (by lowering blood sugar)8 
  • Inhibit the growth of certain types of cancer cells9 

Lion's Mane Dosage 

There's no standard dosage for Lion's Mane, as it depends on the individual’s body weight, age, health condition, and desired health benefits. 

Generally, it's best to start with a lower dosage and gradually increase it until the desired effect is achieved. But most importantly, it's recommended to consult a healthcare professional before taking this supplement. A healthcare professional may help you choose the best dosage for you. 

However, many safe and effective doses have been noted in existing research! For example, a 2019 study found that taking three 400 mg capsules of Lion's Mane daily for 8 weeks was effective in improving mood and sleep disorders in 77 overweight patients.10

Also, another study found 3 to 5 grams of Lion's Mane per day to be an effective dose for improving cognitive function.11 

Possible Side Effects 

While little research exists on possible side effects of Lion's Mane in humans, most animal studies have reported no adverse side effects, even when administered at high doses.12 

However, there have been reported cases of people experiencing allergic reactions, such as acute respiratory distress syndrome13 and allergic contact dermatitis14, after consuming Lion's Mane. Therefore, people who are allergic to mushrooms should avoid taking this supplement. 

What Is Cordyceps? 

Cordyceps is a type of parasitic fungus that grows on the larvae of insects and is usually found in Southeast Asia's mountainous regions. 

Of the 400-plus species of Cordyceps, Cordyceps sinensis and Cordyceps militaris are the two main species known for their medicinal properties. 

Cordyceps is not only rich in essential vitamins and minerals (including B vitamins, selenium, iron, zinc, and magnesium) but also a source of polysaccharides (which are important for healthy cell function and can help boost the immune system). 

Additionally, cordyceps contain antioxidants, which can help protect the body from free radical damage. 

Health Benefits Of Cordyceps 

Several studies have found that taking Cordyceps can provide a variety of health benefits. Cordyceps has been linked to: 

  • Increased energy and stamina2 
  • Enhanced anti-aging effects15 
  • Reduced inflammation16 
  • Improved heart health17 
  • Anti-tumor effects18

Cordyceps Dosage 

Although there is limited research on the optimal dosage of Cordyceps, in most human trials, Cordyceps is administered in the dosage range of 1,000-3,000mg daily. However, the dosage can vary depending on a person’s needs and health goals. It is important to speak to a healthcare professional before taking any supplement, including cordyceps, to ensure it is safe. 

Also, when taking cordyceps, it is important to start with a lower dose and gradually increase it over time. This will help ensure that your body gets used to the supplement and doesn’t experience any adverse effects. 

Possible Side Effects 

Cordyceps is generally safe and well-tolerated, with no known serious side effects. In fact, due to its safety profile, it was officially classified as a drug (for use in hospitals) in the Chinese Pharmacopeia in 1964.19 

What Is CBD? 

Also known as cannabidiol, CBD is a natural compound found in the hemp plant. It is one of the most studied compounds in the cannabis plant family and has been found to have a wide range of potential health benefits. 

Unlike Tetrahydrocannabinol (THC) - the main psychoactive compound in cannabis plants, CBD is not psychoactive. This means it will not get you “high” like THC. This makes it a popular choice for those looking to experience the health benefits of cannabis without any psychoactive effects.

Health Benefits Of CBD 

As one of the most studied compounds in the cannabis family, CBD has been found to provide a wide range of potential health benefits. These include: 

  • Reduced inflammation20 
  • Relief from pain and discomfort21 
  • Ease of anxiety and depression symptoms22 
  • Anti-seizure properties23 
  • Inhibition of tumor cells growth24 

However, to reap these benefits, it is important to purchase your CBD products from a reputable source like BATCH! Our high-quality CBD products are free from harmful additives and tested for purity and potency by third-party labs. 

So, visit our shop today and get started on the path to better health with high-quality CBD! 

CBD Dosage 

The exact dosage of CBD depends on a variety of factors, including a person's weight, age, and metabolism, as well as the conditions and symptoms a person is trying to treat. 

However, the general rule of thumb is to start with a low dose of CBD (such as 5-10mg per day) and increase it gradually until you find the right dose for you. 

Also, it’s recommended to speak to a healthcare professional before taking CBD. A healthcare professional can advise you on the optimal dosage based on your needs and health goals. 

Possible Side Effects 

CBD is generally safe and well-tolerated, but some people may experience mild side effects. According to research, CBD's most common side effects include nausea, fatigue, diarrhea, low blood pressure, changes in weight, dry mouth, and changes in appetite.25 

It is important to note that these are potential side effects; not everyone will experience them. If you experience any of the above symptoms when taking any of these supplements, stop taking them and consult with your doctor. 


Lion's Mane Vs. Cordyceps Vs. CBD: What Do They Have In Common? 

Lion’s Mane, Cordyceps and CBD all have some things in common when it comes to their potential health benefits. 

All three are natural supplements that promote general health and wellness. They are all believed to have anti-inflammatory, antioxidant, and neuroprotective properties. 

Additionally, all three have been studied for their potential to help with stress, anxiety, and depression. 

However, each of these supplements also has its own unique properties and potential health benefits. 

Lion's Mane Vs. Cordyceps Vs. CBD: Key Differences 

While Lion’s Mane, Cordyceps, and CBD are all natural supplements that can help boost health and wellness, they also have some key differences that make them unique. 

To help you better understand these differences, here is a quick comparison between the three. 

Lion’s Mane 

This powerful mushroom contains a wide array of beneficial compounds, including polysaccharides26, beta-glucans27, and hericenones.28 These compounds are believed to have anti-inflammatory, antioxidant, and neuroprotective properties. 

This supplement is typically taken to improve cognitive function, reduce anxiety and depression, and boost immunity. 


A medicinal fungus containing active compounds like polysaccharides29, cordycepin30, and adenosine.31 These compounds are believed to have anti-inflammatory, antioxidant, and immunomodulatory properties. 

This supplement is typically taken to improve energy, reduce fatigue, and boost endurance. 


A cannabinoid found in the cannabis plant. It contains a wide array of beneficial compounds, including terpenes and flavonoids, which are believed to have anti-inflammatory, antioxidant, and neuroprotective properties. 

This cannabinoid is typically taken to reduce anxiety and depression, promote relaxation, and reduce pain. 

Can You Take The Three Of Them Together? 

Yes! It is generally safe to take Lion’s Mane, Cordyceps, and CBD together. In fact, since they all work to improve overall health, taking them together can provide an even greater benefit. 

Lion's Mane and Cordyceps can act as a stimulant to enhance physical activity and recovery from strenuous workouts (by boosting your immune system and reducing inflammation) and also help improve your cognitive function. On the other hand, CBD can help reduce anxiety, improve your mood, and reduce pain. 

However, it is important to always start with a low dose and gradually increase the dosage as needed to avoid potential side effects. 

Additionally, it is recommended to speak to a healthcare professional before taking these supplements together, especially if you are taking any other medications. 

Choosing Which One Is The Best For You 

When deciding which natural supplement is the best for you, it’s important to consider your needs and health goals. While all three supplements offer a wide range of health benefits, each one has its own unique properties and potential health benefits. 

If you’re looking for a supplement to boost your energy and endurance, then Cordyceps would be the best choice. If you’re looking to boost your immunity, improve your cognitive function and reduce anxiety, then Lion’s Mane would be the best choice. And if you are looking to reduce pain, stress, and anxiety, then CBD would be the best choice. 

Ultimately, it is important to understand the key differences between Lion's Mane, Cordyceps, and CBD and choose the one that best fits your needs. Doing so can help you get the most out of these natural supplements and reap their many potential health benefits. 

Final Thoughts 

As we have seen, Lion’s Mane, Cordyceps, and CBD all offer a variety of potential health benefits. But when it comes to choosing the right supplement for you, it is important to understand the key differences between the three and determine which one best fits your needs. By taking into account your individual health goals and needs, you can make the most out of these natural supplements and enjoy their many potential benefits. 

However, if you are specifically interested in CBD supplements, consider BATCH as your trusted source for high-quality, lab-tested products. We offer a wide selection of CBD products, including oils, gummies, softgels, and topicals

So, shop with us today and get the most out of your CBD products!   


What Does Lion's Mane Do To Hormones? 

Lion's Mane has been found to have potential hormone-balancing benefits. It is believed that the compounds in this mushroom can support the endocrine system, which helps regulate hormones and also help reduce stress. 

What Does Lion's Mane Do To The Brain? 

Lion's Mane helps stimulate the growth of brain cells, leading to improved mental clarity and focus. Studies have also suggested that it can help improve memory and prevent cognitive decline.32 

Who Should Not Take Lion's Mane? 

Pregnant or breastfeeding women should avoid taking Lion's Mane. Additionally, people with any underlying medical condition or taking any medications should consult a healthcare professional before taking Lion's Mane. 

Who Should Not Take Cordyceps?

Like Lion's Mane, pregnant or breastfeeding women should avoid taking Cordyceps due to its ability to increase sex hormone levels.33 Additionally, people with any underlying medical condition or taking any medications should consult a healthcare professional before taking Cordyceps. 

Do Cordyceps Work Immediately? 

Cordyceps is known to be a slow-acting supplement, meaning that it takes time to see results. It can take a few weeks before the effects of this mushroom can be seen. 

How Does Cordyceps Make You Feel?

As a natural energy booster for the body and mind, Cordyceps makes you feel energized and alert. It also reduces fatigue, boosts stamina, and improves your overall well-being. 

Are Lion's Mane, Cordyceps, And CBD Legal?

Lion's Mane and Cordyceps are legal in most countries and states. However, in the U.S., CBD is legal under federal law as long as they are hemp-derived and contain less than 0.3% THC. 

Is CBD The Best For Anxiety? 

Yes! CBD is an effective anxiolytic, meaning it can help reduce anxiety. According to one study, CBD significantly reduced anxiety in participants with social anxiety disorder (SAD). In fact, their reduced anxiety levels were comparable to those of the control participants.34 


  1. Li, I.-C., Chang, H.-H., Lin, C.-H., Chen, W.-P., Lu, T.-H., Lee, L.-Y., Chen, Y.-W., Chen, Y.-P., Chen, C.-C., & Lin, D. P.-C. (2020, June 3). Prevention of early alzheimer's disease by Erinacine a-enriched hericium erinaceus mycelia pilot double-blind placebo-controlled study. Frontiers in aging neuroscience. Retrieved from
  2. Chen, S., Li, Z., Krochmal, R., Abrazado, M., Kim, W., & Cooper, C. B. (2010, May). Effect of CS-4 (cordyceps sinensis) on exercise performance in healthy older subjects: A double-blind, placebo-controlled trial. Journal of alternative and complementary medicine (New York, N.Y.). Retrieved from 
  3. Rapin, L., Gamaoun, R., El Hage, C., Arboleda, M. F., & Prosk, E. (2021, June 23). Cannabidiol use and effectiveness: Real-world evidence from a Canadian Medical Cannabis Clinic. Journal of cannabis research. Retrieved from 
  4. M;, F. (n.d.). Chemistry, nutrition, and health-promoting properties of Hericium Erinaceus (lion's mane) mushroom fruiting bodies and mycelia and their bioactive compounds. Journal of agricultural and food chemistry. Retrieved from 
  5. Chong, P. S., Fung, M.-L., Wong, K. H., & Lim, L. W. (2019, December 25). Therapeutic potential of hericium erinaceus for depressive disorder. International journal of molecular sciences. Retrieved from 
  6. Qin M;Geng Y;Lu Z;Xu H;Shi JS;Xu X;Xu ZH; (n.d.). Anti-inflammatory effects of ethanol extract of Lion's mane medicinal mushroom, Hericium Erinaceus (agaricomycetes), in mice with ulcerative colitis. International journal of medicinal mushrooms. Retrieved from 
  7. Sheng, X., Yan, J., Meng, Y., Kang, Y., Han, Z., Tai, G., Zhou, Y., & Cheng, H. (2017, March 22). Immunomodulatory effects of hericium erinaceus derived polysaccharides are mediated by intestinal immunology. Food & function. Retrieved from 
  8. Zhang C;Li J;Hu C;Wang J;Zhang J;Ren Z;Song X;Jia L; (n.d.). Antihyperglycaemic and organic protective effects on pancreas, liver and kidney by polysaccharides from hericium erinaceus SG-02 in streptozotocin-induced diabetic mice. Scientific reports. Retrieved from 
  9. Kim, S. P., Kang, M. Y., Choi, Y. H., Kim, J. H., Nam, S. H., & Friedman, M. (2011, June). Mechanism of hericium erinaceus (yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells. Food & function. Retrieved from 
  10. Vigna, L., Morelli, F., Agnelli, G. M., Napolitano, F., Ratto, D., Occhinegro, A., Di Iorio, C., Savino, E., Girometta, C., Brandalise, F., & Rossi, P. (2019, April 18). hericium erinaceus improves mood and sleep disorders in patients affected by overweight or obesity: Could circulating Pro-BDNF and BDNF be potential biomarkers? Evidence-based complementary and alternative medicine : eCAM. Retrieved from .
  11. Spelman, K., Sutherland, E., & Bagade, A. (2018, December 6). Herbal Medicine for alzheimer's disease: Lion's mane (hericium erinaceus). Restorative Medicine. Retrieved from 
  12. Li IC;Chen YL;Lee LY;Chen WP;Tsai YT;Chen CC;Chen CS; (n.d.). Evaluation of the toxicological safety of Erinacine a-enriched hericium erinaceus in a 28-day oral feeding study in Sprague-Dawley Rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. Retrieved from
  13. Nakatsugawa M;Takahashi H;Takezawa C;Nakajima K;Harada K;Sugawara Y;Kobayashi S;Kondo T;Abe S; (n.d.). Hericium erinaceum (yamabushitake) extract-induced acute respiratory distress syndrome monitored by serum surfactant proteins. Internal medicine (Tokyo, Japan). Retrieved from 
  14. Maes MF;van Baar HM;van Ginkel CJ; (n.d.). Occupational allergic contact dermatitis from the mushroom white pom pom (hericium erinaceum). Contact dermatitis. Retrieved from 
  15. Li XT;Li HC;Li CB;Dou DQ;Gao MB; (n.d.). Protective effects on mitochondria and anti-aging activity of polysaccharides from cultivated fruiting bodies of Cordyceps militaris. The American journal of Chinese medicine. Retrieved from
  16. Park, S.-Y., Jung, S.-J., Ha, K.-C., Sin, H.-S., Jang, S.-H., Chae, H.-J., & Chae, S.-W. (2015). Anti-inflammatory effects of cordyceps mycelium (paecilomyces hepiali, CBG-CS-2) in raw264.7 murine macrophages. Oriental pharmacy and experimental medicine. Retrieved from
  17. Yan, X.-F., Zhang, Z.-M., Yao, H.-Y., Guan, Y., Zhu, J.-P., Zhang, L.-H., Jia, Y.-L., & Wang, R.-W. (2013, November). Cardiovascular protection and antioxidant activity of the extracts from the mycelia of cordyceps sinensis act partially via adenosine receptors. Phytotherapy research : PTR. Retrieved from
  18. HX;, N. T. B. W. (n.d.). Pharmacological actions of Cordyceps, a prized folk medicine. The Journal of pharmacy and pharmacology. Retrieved from
  19. Dong, C., Guo, S., Wang, W., & Liu, X. (2015, May 21). Cordyceps industry in China. Mycology. Retrieved from,1998).,Zhang%20et%20al. 
  20. Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2019, December 25). Antioxidative and anti-inflammatory properties of Cannabidiol. Antioxidants (Basel, Switzerland). Retrieved from 
  21. Argueta, D. A., Ventura, C. M., Kiven, S., Sagi, V., & Gupta, K. (2020, April 30). A balanced approach for cannabidiol use in chronic pain. Frontiers in pharmacology. Retrieved from 
  22. Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015, October). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. Retrieved from 
  23. CBD products may help people with epilepsy better tolerate anti-seizure medications. Johns Hopkins Medicine Newsroom. (2021, August 11). Retrieved from 
  24. B;, P. M. G. J. S. (n.d.). Cannabinoids - a new weapon against cancer? Postepy higieny i medycyny doswiadczalnej (Online). Retrieved from 
  25. Iffland, K., & Grotenhermen, F. (2017, June 1). An update on safety and side effects of Cannabidiol: A review of Clinical Data and relevant animal studies. Cannabis and cannabinoid research. Retrieved from 
  26. Friedman, M. (2016, November 29). Mushroom Polysaccharides: Chemistry and Antiobesity, antidiabetes, anticancer, and antibiotic properties in cells, rodents, and humans. Foods (Basel, Switzerland). Retrieved from,attributed%20to%20them%20%5B22%5D
  27. Mirończuk-Chodakowska, I., Kujawowicz, K., & Witkowska, A. M. (2021, November 6). Beta-glucans from fungi: Biological and health-promoting potential in the COVID-19 pandemic era. Nutrients. Retrieved from 
  28. Kushairi, N., Phan, C. W., Sabaratnam, V., David, P., & Naidu, M. (2019, August 1). Lion's mane mushroom, hericium erinaceus (bull.: Fr.) pers. suppresses H2O2-induced oxidative damage and LPS-induced inflammation in HT22 hippocampal neurons and BV2 microglia. Antioxidants (Basel, Switzerland). Retrieved from 
  29. YF;, X. (n.d.). Effect of polysaccharide from cordyceps militaris (Ascomycetes) on physical fatigue induced by forced swimming. International journal of medicinal mushrooms. Retrieved from,of%20biological%20and%20pharmacological%20properties. 
  30. Ashraf, S. A., Elkhalifa, A. E. O., Siddiqui, A. J., Patel, M., Awadelkareem, A. M., Snoussi, M., Ashraf, M. S., Adnan, M., & Hadi, S. (2020, June 12). Cordycepin for Health and wellbeing: A potent bioactive metabolite of an entomopathogenic cordyceps medicinal fungus and its nutraceutical and therapeutic potential. Molecules (Basel, Switzerland). Retrieved from 
  31. TH;, T. Y. J. L. L. C. T. (n.d.). Pharmacokinetics of adenosine and Cordycepin, a bioactive constituent of cordyceps sinensis in rat. Journal of agricultural and food chemistry. Retrieved from 
  32. Ratto, D., Corana, F., Mannucci, B., Priori, E. C., Cobelli, F., Roda, E., Ferrari, B., Occhinegro, A., Di Iorio, C., De Luca, F., Cesaroni, V., Girometta, C., Bottone, M. G., Savino, E., Kawagishi, H., & Rossi, P. (2019, March 27). hericium erinaceus improves recognition memory and induces hippocampal and cerebellar neurogenesis in frail mice during aging. Nutrients. Retrieved from 
  33. Tuli, H. S., Sandhu, S. S., & Sharma, A. K. (2014, February). Pharmacological and therapeutic potential of cordyceps with special reference to Cordycepin. 3 Biotech. Retrieved from 
  34. Bergamaschi MM;Queiroz RH;Chagas MH;de Oliveira DC;De Martinis BS;Kapczinski F;Quevedo J;Roesler R;Schröder N;Nardi AE;Martín-Santos R;Hallak JE;Zuardi AW;Crippa JA; (n.d.). Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. Retrieved from
March 10, 2023 — Griffin Lynch

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