The Lion's Mane mushroom is a fungus that has been used in traditional medicine for centuries. It is said to offer a range of benefits, including increased focus, clarity, and a sense of calm. In recent years, scientific research has revealed the incredible potential of the Lion's Mane mushroom, from its cognitive-enhancing effects to its potential to improve digestive and immune health. But if you’re seeking to leverage it in your life, what might you expect? How exactly might it benefit you?

 In this article, we will explore the spiritual benefits of Lion's Mane, its bioactive compounds, and the potential health benefits of this remarkable mushroom to answer all of your questions.

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Read More: Top 5 Lion's Mane Gummies of 2024

What Are Lion's Mane Mushrooms?

Lion’s Mane mushrooms are a type of edible mushroom that has been used in traditional medicine for centuries. Native to North America, Europe, and Asia, they are most commonly found growing on hardwood trees. They are also known as bearded tooth mushrooms, pom pom mushrooms, and hedgehog mushrooms.

These mushrooms have a unique appearance, with a long, shaggy white or yellowish-white surface that resembles a lion’s Mane. They are known to have a mild, sweet flavor and a slightly crunchy texture.

How Do Lion's Mane Mushrooms Work? 

While Lion’s Mane mushrooms have become extremely popular for their reported health benefits, we still don’t quite understand how they may interact with the body. That being said, Lion’s Mane is said to help the body grow new brain cells, support gut health, improve nerve development and functionality, and beyond. Still, more research needs to be conducted before we can draw any definitive conclusions as to how the compounds in Lion’s Mane affect physiology.

Lion’s Mane Vs. Reishi 

Mushrooms as a whole have made waves in the health and wellness industry in recent years. Two key players, Lion’s Mane and Reishi, are often incorporated into wellness routines. But how do these mushrooms stack up against each other? How are they the same, and how do they differ? Here’s a quick overview to help you better understand these two popular fungi. 

Appearance: Lion’s Mane is a shaggy, round, large white mushroom, while Reishi has more of a kidney or fan shape, characterized by its reddish/orange hue and shiny top.

Growth: Lion’s Mane tends to grow in the late summer or early fall, growing only hardwood trees like oak, beech, and maple. Reishi, on the other hand, is more varied. Some grow in subtropical climates while others thrive in more temperate climates. Some prefer hardwood trees like Lion’s Mane does while others grow primarily on coniferous trees.

Potential Benefits: Lion’s Mane is said to offer mood benefits, immune system benefits, and anti-inflammatory and antioxidant properties. These two share many of the same potential benefits, but Reishi may also boost energy, increase stamina and strength, and lower cholesterol.

Side Effects: Some side effects of Lion’s Mane include nausea, abdominal discomfort, and skin rash. Some side effects of Reishi include headache, dry mouth, dizziness, and beyond. The potential for allergic reactions exist with both, so it’s important to keep this in mind as well. 

Bioactive Compounds Of The Lion's Mane 

Lion's Mane mushrooms are known to contain a variety of bioactive compounds, including erinacerin and hericenones, polysaccharides, polypeptides, 1,3 1,6 beta-glucans, and digestive enzymes. Let’s take a closer look at each of these to better understand what role they may play in the body once you’ve consumed Lion’s Mane.

Erinacerin And Hericenones 

Erinacerin and hericenones are two bioactive compounds found in Lion’s Mane mushrooms. Erinacerin is a polyphenol that may help reduce inflammation and may even reduce the risk of certain diseases. Hericenones are responsible for the mushroom's anti-inflammatory and antioxidant properties.

Erinacerin and hericenones have also been said to help improve nerve growth factor (NGF). NGF is a protein that helps promote the growth and repair of nerve cells. Both Erinacerin and hericenones may help increase the levels of NGF in the brain, which could help improve cognitive function. 


Polysaccharides are a type of complex carbohydrate found in different foods, including grains, fruits, and vegetables. They are composed of long chains of simple sugars, such as glucose and fructose, linked together in many ways and are important for a variety of bodily functions, like providing energy and aiding digestion.

Studies suggest that polysaccharides may help to support the immune system, reduce inflammation, and protect against oxidative damage1. Lion's Mane mushrooms contain a variety of polysaccharides, including glucans, mannans, and xylans, which are thought to be responsible for some of the mushroom's potential health benefits. 


Polypeptides are a type of molecule found in Lion's Mane mushrooms that are made up of chains of amino acids linked together by peptide bonds. They are important for the functioning of the body, as they play a role in many processes, such as enzyme production, muscle contraction, and hormone regulation.

Polypeptides are also important for the immune system, as they can interact with the body's cells to help fight off pathogens and other foreign invaders. These molecules are also involved in the digestion of proteins and other nutrients, as they are able to break down large molecules into smaller ones, making them easier to absorb. 

1,3 1,6 Beta-Glucans 

1,3 1,6 beta-glucans are a type of polysaccharide found in the cell walls of fungi, including the Lion's Mane mushroom. These beta-glucans are made up of glucose molecules linked together in a specific pattern. Studies have shown that consuming these beta-glucans can help to improve gut microbiota, reduce inflammation, and support digestive health2.

Additionally, they may help to reduce cholesterol levels, which can greatly improve heart health. The 1,3 1,6 beta-glucans found in Lion's Mane mushrooms are believed to be responsible for many of the health benefits associated with this medicinal mushroom. These beta-glucans are also believed to help support the body's natural defense system, improve gut health, and reduce cholesterol levels.

Digestive Enzymes 

Digestive enzymes are a type of protein found in Lion's Mane mushrooms that aid in the digestion of food. They help break down complex carbohydrates, proteins, and fats into simpler forms that can be more easily absorbed by the body. Additionally, they help to reduce inflammation in the digestive tract and improve absorption of essential vitamins and minerals, and may help to reduce the risk of certain conditions like digestive tract inflammation. Therefore, Lion's Mane mushrooms may be a great addition to any diet to improve overall digestive health.

Lion's Mane Spiritual Benefits

Lion's Mane mushrooms have long been used in traditional medicines for their spiritual benefits, such as bringing clarity, focus, and a sense of calm. These reported spiritual benefits may be due to the bioactive compounds in the mushroom, which act on the body and mind. The mushrooms are said to open the mind and awaken the senses, allowing us to better appreciate the beauty of nature. The bioactive compounds in the mushroom may also have an effect on our emotional well-being, reducing stress and anxiety.

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Connection To Nature 

Lion's Mane mushrooms are believed to have a unique ability to help us become more aware of our environment and appreciate the beauty of nature. The mushroom has been used for centuries in traditional medicine, and it is thought to be a powerful tool for spiritual growth.

By consuming Lion's Mane, some have said they’ve gained a deeper understanding of their place in the world and their connection to the natural world. It is also said to help us become more mindful of our thoughts and actions, as well as our emotions. 

Mind Awakening 

The Lion's Mane mushroom's bioactive compounds are believed to contribute to the spiritual benefits it has to offer. Erinacerin and hericenones help to “awaken the mind”, while polysaccharides increase the production of acetylcholine, which serves to improve cognitive functions and sharpen the mind. Polypeptides help to increase the production of serotonin, which may support better mood and sleep.

Meditation Aid 

Meditation is an ancient practice used to gain greater insight into the self, connect with the divine, and cultivate a sense of inner peace. Studies have shown that the polypeptides found in Lion's Mane mushrooms can help to reduce anxiety and stress, increase cognitive performance, reduce the effects of depression, and increase feelings of connection with nature3. 

Emotional Healing 

Emotional healing is one of the most profound effects of taking Lion's Mane. It has been found to have a positive effect on serotonin levels in the brain, which can improve mood and reduce feelings of anxiety or depression. It also has the potential to reduce cortisol levels, which is the hormone responsible for stress. 

Health Benefits Of Lion's Mane 

Understanding all the different compounds contained in Lion’s Mane is an excellent starting point, but it’s important to look at each of the individual health benefits if you want to see exactly how it might support you. Here are some of the top reported health benefits of Lion’s Mane:

Positive Mood And Improved Cognitive Function 

Research is currently being conducted to determine whether or not Lion’s Mane can serve to improve cognitive health by reducing the symptoms of mental health disorders like anxiety and depression. Some studies have found that supplementing with the extract for four weeks reduced symptoms of anxiety and depression in participants with mild cognitive impairment and major depressive disorder.4 That being said, it’s important to remember that Lion’s Mane is not a suitable replacement for traditional talk therapy and medication. 

May Benefit Gut Health 

The Lion's Mane mushroom has been studied for its potential benefits to gut health. The polysaccharides, polypeptides, 1,3 1,6 beta-glucans, and digestive enzymes found in Lion's Mane may help to reduce inflammation in the gut, protect the gut lining, reduce the growth of harmful bacteria, and improve digestion. 

Immune Function Support 

Lion's Mane may support and strengthen the body's immune system. This is due to the polysaccharides, polypeptides, and 1,3 1,6 beta-glucans found in the mushroom. These compounds have anti-inflammatory and antioxidant properties, which may help to protect the body from free radical damage. The polysaccharides activate the body's natural killer cells, which could help to boost the immune system and make it more effective at fighting off viruses, bacteria, and other pathogens.

Could Benefit Cardiovascular Health 

Lion's Mane mushrooms may offer potential cardiovascular benefits due to their high levels of bioactive compounds and antioxidants, such as Erinacerin and Hericenones, polysaccharides, polypeptides, Beta-Glucans, and digestive enzymes. Erinacerin and Hericenones might reduce cholesterol levels, decrease inflammation, and improve blood vessel health. 

How To Take Lion's Mane? 

Lion’s Mane can be taken in a wide variety of ways, including cooking the fresh mushrooms or using supplements like capsules, gummies, or incorporating powder into your favorite beverages and recipes.

If you choose to cook Lion’s Mane, keep in mind that Lion’s Mane tends to be somewhat hard to find and more expensive than other mushrooms, hovering around $14 to $16 per pound. You should store it in the fridge in a paper bag, eating it soon after you’ve purchased it. Take care to wash, prepare, and cook them correctly so that you eliminate any dirt or germs prior to consuming them.

Lion’s Mane supplements are often more versatile, less expensive, and easier to use. As long as you only purchase Lion’s Mane supplements from reputable vendors and keep your supplements in a cool, dry place, you should have no trouble enjoying them!

Recommended Dosage 

When it comes to taking Lion’s Mane, it is important to start with a low dose and gradually increase it as your body becomes accustomed to it. Generally, a dose of 500-1000mg per day is recommended for adults. Note that Lion’s Mane is not recommended for pregnant or breastfeeding women, as there is not enough evidence to support its safety for these populations.

It should not be taken in higher doses than recommended, as it can cause side effects such as nausea and vomiting. Take Lion’s Mane supplements with food rather than on an empty stomach, in order to maximize its absorption. It is critical to consult with a doctor before taking Lion's Mane as it may interact with certain medications or supplements.

Discover The Remarkable Benefits Of Lion's Mane With Batch 

Lion’s Mane mushrooms have a lot to offer, but how can you get started on your own mushroom exploration journey? Start here with BATCH’s Brain Boost Mushroom Gummies!

BATCH’s Brain Boost gummies are formulated with three key ingredients: 300 milligrams of Lion’s Mane, 100 milligrams of Cordyceps, and 10 milligrams of Reishi. This unique blend of functional mushrooms and botanicals is designed to support memory, focus, and brain function, bolstering brain and nervous system health. Of course, we also take our unique approach to this formulation, offering benefits like: 

Gummies formulated 100% from the cap of the mushrooms (that’s where all the good stuff is).

A final product made using USDA-certified mushrooms grown on natural substrate. 

A dual extraction process to include all of the beneficial compounds and hyper-concentrated extracts. 

No psychedelic or intoxicating effects!

If you want calm energy, more focus, and better brain health, try our Brain Boost Mushroom Gummies today!

Final Thoughts 

If you are looking for a natural way to boost your health and well-being, then Lion's Mane mushrooms may be worth considering. Not only will your body thank you for its’ wide range of pharmaceutical properties but your mind will be more focused and calm and help you make better decisions in life.

Are you ready to take your wellness journey to the next level? You deserve only the best, and BATCH is here to deliver! We take great care to monitor every step of the production process, helping us offer greater transparency to you and guarantee both purity and potency. No matter what you’re shopping for, you can rest assured that you’re getting premium-quality products that contain no fillers or additives and have been third-party tested for your satisfaction. 

We also make shopping simple with free shipping on orders over $25 and 25% off of your order when you subscribe and save. Shop now or get in touch with one of our specialists if you need any help!

Want to learn more about Lion’s Mane mushroom?  Check out our past blogs:

Unlocking The Potential: Functional Mushrooms For Optimizing Brain Health

Exploring The Pros And Cons Of Lion's Mane Vs. Cbd For Sleep

Lion's Mane Nootropic For Adhd: Does It Work?


Can Lion's Mane give you energy? 

Lion's Mane mushrooms are not known to directly provide energy. However, they may help support energy levels indirectly. Lion's Mane mushrooms may support cognitive functions, including focus, concentration, and memory. These benefits could help improve energy levels, as they are said to reduce mental fatigue and improve mental clarity.

How effective is Lion's Mane? 

The efficacy of Lion’s Mane can depend on a wide range of factors. This includes the dose you’re taking, how your body responds to Lion’s Mane, if any other compounds are contained within your supplements, and more. Keep all of this in mind when you incorporate Lion’s Mane into your daily routine. 

Can I have Lion's Mane every day? 

It is generally considered safe to take Lion's Mane mushrooms in supplement form on a daily basis. However, it is recommended to start with a smaller dosage and gradually increase as needed. It is important to follow the recommended dosage instructions on the supplement label and to either reduce your dose or cease consumption if you observe major side effects or an allergic reaction. 

Is Lion's Mane better at night or day? 

Lion's Mane mushrooms may be taken at any time of the day. However, it is recommended to take them with food to improve absorption, which means that you’re more likely to consume them alongside your meals (or even with your meals if you plan on cooking them).

Is Lion's Mane good for depression? 

Lion’s Mane mushroom may have mood benefits, and some studies have pointed to its potential to reduce symptoms of depression. However, it shouldn’t be used as a replacement for medications or if you haven’t yet been diagnosed. Bring this up with your psychologist to learn more about whether or not it’s right for you.

Who should not take Lion's Mane? 

Lion's Mane mushrooms are generally considered safe for most people. However, people who are allergic to mushrooms should avoid taking them. Additionally, pregnant and breastfeeding women should consult their doctor before taking Lion's Mane mushrooms.


  1. Murphy EJ, Fehrenbach GW, Abidin IZ, Buckley C, Montgomery T, Pogue R, Murray P, Major I, Rezoagli E. Polysaccharides-Naturally Occurring Immune Modulators. Polymers (Basel). 2023 May 19;15(10):2373. doi: 10.3390/polym15102373. PMID: 37242947; PMCID: PMC10222865.
  2. Singh RP, Bhardwaj A. β-glucans: a potential source for maintaining gut microbiota and the immune system. Front Nutr. 2023 May 5;10:1143682. doi: 10.3389/fnut.2023.1143682. PMID: 37215217; PMCID: PMC10198134.
  3. Julson, Erica. “9 Health Benefits of Lion’s Mane Mushroom (plus Side Effects).” Healthline, 7 Feb. 2023,
  4. Nagano M;Shimizu K;Kondo R;Hayashi C;Sato D;Kitagawa K;Ohnuki K; (n.d.). Reduction of depression and anxiety by 4 weeks hericium erinaceus intake. Biomedical research (Tokyo, Japan).

June 19, 2023 — Griffin Lynch

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